Spatially controlled chemistry using remotely guided nanoliter scale containers.
نویسندگان
چکیده
In this communication we describe a new chemical encapsulation and release platform using 3D microfabricated nanoliter scale containers with controlled porosity. The containers can be fabricated of magnetic materials that allow them to be remotely guided using magnetic fields. The favorable attributes of the containers that include a versatile highly parallel fabrication process, precisely engineered porosity, isotropic/anisotropic chemical release profiles, and remote magnetic guiding provide an attractive platform for engineering spatially controlled chemical reactions in microfluidic systems.
منابع مشابه
Advancing microarray assembly with acoustic dispensing technology.
In the assembly of microarrays and microarray-based chemical assays and enzymatic bioassays, most approaches use pins for contact spotting. Acoustic dispensing is a technology capable of nanoliter transfers by using acoustic energy to eject liquid sample from an open source well. Although typically used for well plate transfers, when applied to microarraying, it avoids the drawbacks of undesire...
متن کاملUser-loaded SlipChip for equipment-free multiplexed nanoliter-scale experiments.
This paper describes a microfluidic approach to perform multiplexed nanoliter-scale experiments by combining a sample with multiple different reagents, each at multiple mixing ratios. This approach employs a user-loaded, equipment-free SlipChip. The mixing ratios, characterized by diluting a fluorescent dye, could be controlled by the volume of each of the combined wells. The SlipChip design wa...
متن کاملSpatially Explicit Large Area Biomass Estimation: Three Approaches Using Forest Inventory and Remotely Sensed Imagery in a GIS
Forest inventory data often provide the required base data to enable the largearea mapping of biomass over a range of scales. However, spatially explicit estimates ofabove-ground biomass (AGB) over large areas may be limited by the spatial extent of theforest inventory relative to the area of interest (i.e., inventories not spatially exhaustive), orby the omission of inventory attributes requir...
متن کاملImpact of Spatial Scale on Remotely Sensed Evapotranspiration Estimates from Heterogeneous Land Surfaces
Remote sensing can provide estimates of spatially distributed actual evapotranspiration (ET) at different spatial scales. Methods that combine remotely sensed observations with other ground-based information on land and atmospheric properties usually allow improved estimates of spatially distributed evapotranspiration (ET) than when remotely sensed data are used alone. Spatial resolution of rem...
متن کاملThree-dimensional Manipulations of Nanoliter Water-drops on Open Platforms Using Magnetically Controlled Hydrophobic Ferro-drops
Here we present a novel and extremely simple method that can manipulate magnetic label-free nanoliter water-drops using micro-nanoliter magnetically controlled hydrophobic ferro-drops used as magnetic mediators. Water-drops and ferro-drops can be dynamically connected under interface force of water/oil, allowing water-drops to be rapidly motioned on threedimensional open platforms and transferr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 128 35 شماره
صفحات -
تاریخ انتشار 2006